PHARMACOLOGY

General Module

Course Sheet

Academic Year of enrolment:

2016/2017

Type of Course:

Characterising

Optional/Mandatory:

Compulsory

Degree:

5-year Single Cycle Master's Degree Programme in VETERINARY MEDICINE

Disciplinary Sector:

Veterinary Pharmacology and Toxicology

Is part of:

PHARMACOLOGY AND TOXICOLOGY

Credits:

Programme Year:

Professor and Collaborators:

DEMONTIS Maria Piera

Hours of classroom activity:

Prerequisites:

Student must have passed Microbiology and General pathology exam

AF code:

40000867

Teaching period

Single Annual Cycle

Objectives

During the course of Pharmacology are evaluated aspects related to: the denomination and classification of different active ingredients; the pharmacokinetic and pharmacodynamic characteristics; the study of therapeutic and / or toxic effects, as well as the main therapeutic indications. The student acquires knowledge on the sub-cellular and molecular actions of drugs in correlation with pharmacological effects that constitute the rational requirement of therapy. The course stimulates students to acquire basic knowledge on the action of drugs; to provide the cognitive tools for a good use of the drug; to provide knowledge on the legislation that regulates the use of the veterinary drug (how to prescribe a veterinary drug). In this way the student can develop the necessary skills for a rational and responsible use of the drug in the clinical practice.

Contents

Lectures (42 hours)
General Pharmacology: definitions and efinition and branches of Pharmacology. Origin and nature of drugs. Pharmaceutical formulations. Routes of administration. Pharmacokinetics: absorption, distribution, metabolism and excretion. Drug-protein binding. Principles of pharmacokinetics. Pharmacodynamics: receptor-mediated actions (transduction mechanisms, regulators of the receptor-translation system, drug-receptor interactions) and actions not mediated by receptors. Nature of the pharmacological action and factors able to modify its action. Changes in sensitivity to drugs.
Special Pharmacology: physiopharmacological bases. Neurotransmission drugs. Pharmacology of the autonomic nervous system. Central Nervous System drugs: anesthetics, hypnotics and sedatives, antiepileptics, opioid analgesics, neuroleptics and analectics. Pharmacology of autacoids: histamine and antihistamine drugs; Steroid and non-steroidal anti-inflammatory drugs. Cardiovascular system pharmacology. Renal Pharmacology. Respiratory System Pharmacology. Pharmacology of the gastrointestinal system.
Practical training (18 hours)
Practical training sessions are carried out in groups of 3; each group consists of a number of 10-12 students to better guarantee the quality of teaching.
Topics are established before the start of the course.
- Calculation of dosage of pharmaceutical formulations. Calculation of the dilutions of pharmaceutical formulations. Galenic preparations for veterinary use. Use of the veterinary drug manual for the prescription of drugs. Experimental animal models (animal housing for experimental use). Enzymatic assays. Veterinary didactic hospital (importance of dosage and therapeutic response to the administration of drugs with evaluation of clinical modifications, electronic prescription).

Recommended Bibliography

1. Farmacologia Veterinaria - CARLI – ORMAS – RE – SOLDANI –Idelson-Gnocchi, 2009
2. Trattato di Farmacologia - L. ANNUNZIATO – G. DI RENZO, Idelson-Gnocchi, 2016
3. Le Basi della Farmacologia – Howland R.D., Mycek M.J. zanichelli, 2013
4. RIVIERE J.E., Papich M.G. - Veterinary Pharmacology and Therapeutics. - Wiley-Blackwell. 2012
Lectures'' slides are made available for consultation

PHARMACOLOGY

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Course year: 2

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Course year: 4

Course year: 5

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PHARMACOLOGY