Targets of drugs: proteins, enzymes, receptors. Receptors and signal transduction. Nucleic acids.
Pharmacodynamics. Enzymes as drugs targets, receptors as drug targets, other targets.
Pharmacokinetics. Adsorption, Distribution, Methabolism, Excrection.
Routes of administration and dosage forms.
Drug discovery. Lead compounds identification and optimization. Preclinical and clinical trials, patenting, chemical development.
Synthetic approaches to the synthesis of drugs, molecular modelling, structure-activity relationship.