MEDICAL GENETICS
The aim of this course in providing a student with a thorough grounding in the basics of human genetics. The student will acquire advanced knowledge about the organization of nuclear and mitochondrial genomes and about DNA variability.
Additionally, the student will learn the classical concepts of inheritance transmission patterns, the principles of genetic characterization and multifactorial traits and diseases.
A special focus of the course will be given on the interaction of genes and environment in the complex biological systems of the human body under normal conditions and diseases.
Last, the course will be conducted through an experimental approach to develop the scientific methodology, skills that will increase the student abilities in clinical decisions and problem solving.
Genes in families and populations
Structure and function of the human genome
Model organisms, comparative genomics and evolution
Gene expression
Human genetic variability and its consequences
Strategies for the identification of disease genes in monogenic and complex diseases
Genetic approaches for disease therapy
Cancer genetics
Gene / environment interactions in human diseases and traits
Farmacogenomics
Bioinformatics tecniques
Russell et al, Elementi di Genetica, EdiSES