Chemistry and propedeutical Biochemistry
Students must prove: - to know the relationship structure/function of the principal biological molecular classes; - to understand the principles of enzymology, basic principals of kinetics and regulation of enzymatic functions; - to understand the process of oxidative phosphorylation and mitochondrial synthesis of ATP; - to describe the biochemical mechanisms at the base of metabolism and its regulation; - to have basic knowledge of biochemical/metabolic properties of the principal organs useful for the comprehension of the physiopathological aspects connected with the functions of the organ.
Structural Biochemistry: Macromolecules and monomeric subunits Relationship between biomolecules and cellular structures Composition of living matter Water homeostasis Chromoproteins, oxygen carriers Enzymes Fee radicals and reactive oxygen species Bioenergy: ATP production and oxidative phosphorylation Metabolic biochemistry: Glucidic metabolism Amino acid and protein metabolism Lipid metabolism Functional Biochemistry Cellular Biochemistry Cell communication and signal transduction: Integration of glucidic and lipid metabolism Energetic substrates and nutritional requirements Cycle nutrition/fasting Mellitus diabetes and obesity
Biochimica Medica, IV edizione – Siliprandi & Tettamanti – PICCIN Biochimica con aspetti clinici, 5/e – Thomas M. Devlin – EdiSES Biochmica, Settima edizione- Jeremy M. Berg, John L. Tymoczko, Lubert Stryer _ ZANICHELLI
Theoretical lessons, use of multimedia tools. During the classes, students are encouraged to ask questions on the covered subjects. Written exams will be done during the course either with multiple choice or open questions.
