Chemistry and propedeutical Biochemistry
Students must prove: - to know the relationship structure/function of the principal biological molecular classes; - to understand the principles of enzymology, basic principals of kinetics and regulation of enzymatic functions; - to understand the process of oxidative phosphorylation and mitochondrial synthesis of ATP; - to describe the biochemical mechanisms at the base of metabolism and its regulation; - to have basic knowledge of biochemical/metabolic properties of the principal organs useful for the comprehension of the physiopathological aspects connected with the functions of the organ.
Structural Biochemistry: Macromolecules and monomeric subunits Relationship between biomolecules and cellular structures Composition of living matter Water homeostasis Chromoproteins, oxygen carriers Enzymes Fee radicals and reactive oxygen species Bioenergy: ATP production and oxidative phosphorylation Metabolic biochemistry: Glucidic metabolism Amino acid and protein metabolism Lipid metabolism Functional Biochemistry Cellular Biochemistry Cell communication and signal transduction: Integration of glucidic and lipid metabolism Energetic substrates and nutritional requirements Cycle nutrition/fasting Mellitus diabetes and obesity
Biochimica Medica, IV edizione – Siliprandi & Tettamanti – PICCIN Biochimica con aspetti clinici, 5/e – Thomas M. Devlin – EdiSES Biochmica, Settima edizione- Jeremy M. Berg, John L. Tymoczko, Lubert Stryer _ ZANICHELLI