General concepts related to drugs and toxic substances about kinetics and dynamics, with reference to the routes of introduction, absorption, distribution, metabolism and elimination; classification of xenobiotics, action sites and mechanisms of action. Evaluation of the therapeutic use of the main classes of drugs on various systems, of undesirable and toxic effects, of useful and harmful interactions and of associations useful in the clinical practice. In particular the drugs of the nervous system, cardiovascular, respiratory, renal, digestive and drugs of the autacoid system. Evaluation of therapeutic use, toxicity and drug resistance of the main classes of antibiotics and chemotherapeutics, anthelmintic, antiprotozoal, ectoparasiticides. Evaluation of the main classes of xenobiotics that can cause intoxication, in particular the toxicology of pesticides, inorganic and organic compounds, mycotoxins and environmental toxicology.