Basic knowledge of Biochemistry
t the end of this course, the student will know the role of biochemical parameters in biological samples as well as in vivo at different levels of structural organization, from single molecules to cells, and in the whole organism both in the humans and in animals. The student will be able to know and manage: the role of the biochemical parameters that are the basis of inherited diseases and the quality control system; the automation technologies for the quantitative and qualitative analysis of the biochemical parameters useful for clinical diagnostics.
Introduction to Clinical Biochemistry. Overview of basic biochemical methodology The biological samples: handling and storage, Analytical and biological variation, Quality control, Laboratory management.
Function and diagnostic approach of organs and tissues: kidney, heart, liver,
Metabolomics: Glucose metabolism and Lipid Metabolism. Tumor markers.
Ciaccio, Lippi, Biochimica Clinica e Medicina di Laboratorio, Edises
Federici G. et al., Medicina di Laboratorio, ed. McGraw-Hill.
Antonozzi, Gulletta, Medicina di Laboratorio Logica e patologia Clinica Piccin
Practical training at the Clinical Biochemistry and Biotechnology laboratory of the Biomedical Sciences Department. Before each practical section, short in-class lectures will illustrate the laboratory experiments (rationale, experimental approach, protocols, data analysis and interpretation).
Availability of the lectures slides