Definition of the concepts of health, homeostasis, etiology, pathogenesis and disease. Environmental pathology: etiologic agents of physical, chemical and mechanical causes injury. Cellular Pathology: basic mechanisms of damage, an adaptive cellular responses, intracellular regressive processes, reversible and irreversible damage and cellular death by necrosis and apoptosis. Acute and chronic inflammation. Immunity: innate immunity, acquired immunity, humoral immune response, major histocompatibility complex, the complement system, cell-mediated immune response. Oncology: general characteristics of neoplastic development, benign and malignant tumors, etiology of cancer, oncogenes and tumor suppressor genes, the metastatic process.