BIOLOGY, BIOCHEMISTRY AND GENERAL MICROBIOLOGY

Integrated educational activity

Course Sheet

Academic Year of enrolment:

2019/2020

Optional/Mandatory:

Compulsory

Degree:

Bachelor's Degree Programme in NURSING

Language:

Italian

Moduls:

BIOCHEMISTRY WITH ELEMENTS OF CHEMISTRY FOR MEDICINE

2 credits
MICROBIOLOGY AND CLINICAL MICROBIOLOGY

1 credits
APPLIED BIOLOGY

2 credits
CLINICAL BIOCHEMISTRY

1 credits
MEDICAL GENETICS

1 credits

Credits:

Programme Year:

Hours of classroom activity:

Prerequisites:

Biologia e Biochimica background

AF code:

40004053

Assessment Methods

Verification of learning:

During the course the student will perform written tests. The exam sessions during the academic year will expect an oral exam.

Teaching period

First semester

Objectives

At the end of the course the student will acquired basic knowledge on the structural, functional and dynamic properties of the fundamental unit of living organisms both of prokaryotic and of eukaryotes cells, in its various expressions, of the main constituents of this and of the extracellular milieu, with particular reference to the chemical composition and to the metabolic transformations to which the constitutive biomolecules undergo under physiological conditions, to the life cycle and to the principles that manage the transmission of the hereditary traits of living organisms. Within the overall training, the course aims to provide the learner with the knowledge necessary to address the study of other disciplines, including physiology, general pathology and pharmacology, as well as being preliminary to more clinical courses. The student will be able to integrate the theoretical and practical nursing knowledge with the basic biological sciences useful for understanding the complexity of individuals of all ages, groups and communities.
The course proposes an integration of the most current notions of cellular biology, biochemistry, genetics, molecular biology, microbiology and clinical biochemistry, that will provide the student with the necessary tools to get to know and describe in an organic way the structure of eukaryotic cells and their functions.

Contents

The world of the living things. Procaryotic and eukaryotic cells
Biological membrans and cell trafficking
DNA structures and functions
DNA replication genes and genomes
Different types of RNA
RNA synthesis and processing
From genes to protein: Protein synthesis
Cell cycle, mitosis and meiosis
Stem cells and regenerative medicine
The water
electrolytes,
Buffers, buffer systems of the blood
water homeostasis
The amino acids and the peptide bond
The proteins and their various functions
Hemoglobin and oxygen transport
the enzymes
Bioenergetics and oxidative phosphorylation
Structure and metabolism of carbohydrates
Structure and lipid metabolism
Communication between cells and signal transduction
Metabolic effects of insulin and glucagon
Structure and function of bacteria and viruses
Microbiological Diagnostic procedures, pre-analytical and analytical phases
Outline of antimicrobial drugs and resistance
The transmission routes of infections
Endogenous and exogenous infections (in particular Health care-Associated Infections, HAI)
Pathogenesis and diagnosis of principal infections of central nervous, genitourinary, respiratory, cardio-vascular and gastroenteric systems. Hepatitis, HIV
Genes in families and populations
Structure and function of the human genome
Model organisms, comparative genomics and evolution
Gene expression
Human genetic variability and its consequences
Strategies for the identification of disease genes in monogenic and complex diseases
Genetic approaches for disease therapy
Cancer genetics
Gene / environment interactions in human diseases and traits
Farmacogenomics
Bioinformatics tecniques
Introduction to Clinical Biochemistry.
Preanalysis; Blood sampling and storage
Analysis: clinical laboratory automation;
Postanalysis: medical decision making; Quality control, Laboratory management, Assessment of clinical significance of results.
Serum proteins and serum protein electrophoresis patterns.
Measurement of renal function.
Lipids and dyslipoproteinemia. Cardiac injury, atherosclerosis, and thrombotic disease. (Lipoprotein evaluation, homocysteine evaluation)
Clinical enzymology (Evaluation of liver function, Heart Function, Pancreas Function)
Carbohydrates (Biomarkers for diabetes evaluation)

Recommended Bibliography

Bertoldi, Colombo, Magni, Marin, Palestini CHIMICA E BIOCHIMICA, Edises
Solomon
Fondamenti di Biologia, Edises
Principi di Microbiologia Medica , Antonelli,Clementi,Pozzi,Rossolini casa editrice Ambrosiana
Russell et al, Elementi di Genetica, EdiSES
• Stoppini, Bellotti, Biochimica Applicata, Edises
• Antonozzi, Gulletta, Medicina di Laboratorio Logica e patologia Clinica Piccin

Methods of Provision

Conventional

Teaching Methods

Lectures with computer media. Ongoing questions about various topics will be administered. These shall represent self-evaluation by the student, talking points and request of tutoring.
The professor is available to clarify doubts raised by the students and to carry out tutoring support for exam preparation

Contacts/More Information

Readiness to offer individual assistance also in a foreign language (English)
Availability of supporting material and bibliographic references also in a foreign language (English)
Readiness to accept examination of incoming students also in a foreign language (English)

BIOLOGY, BIOCHEMISTRY AND GENERAL MICROBIOLOGY

Course year: 1

Course year: 2

Course year: 3

Search form

BIOLOGY, BIOCHEMISTRY AND GENERAL MICROBIOLOGY