BIOLOGY, BIOCHEMISTRY AND MICROBIOLOGY

Integrated educational activity

Course Sheet

Academic Year of enrolment:

2020/2021

Optional/Mandatory:

Compulsory

Degree:

Bachelor's Degree Programme in MIDWIFERY

Language:

Italian

Moduls:

BIOCHEMISTRY WITH ELEMENTS OF CHEMISTRY FOR MEDICINE

2 credits
MICROBIOLOGY AND CLINICAL MICROBIOLOGY

1 credits
APPLIED BIOLOGY

2 credits
MEDICAL GENETICS

1 credits

Credits:

Programme Year:

Hours of classroom activity:

Prerequisites:

AF code:

40000292

Assessment Methods

Verification of learning:

Bertoldi, Colombo, Magni, Marin, Palestini CHIMICA E BIOCHIMICA, Edises
Solomon
Fondamenti di Biologia, Edises
Principi di Microbiologia Medica , Antonelli,Clementi,Pozzi,Rossolini casa editrice Ambrosiana
Russell et al, Elementi di Genetica, EdiSES
• Stoppini, Bellotti, Biochimica Applicata, Edises
• Antonozzi, Gulletta, Medicina di Laboratorio Logica e patologia Clinica Piccin

Teaching period

First semester

Objectives

At the end of the course the student will acquired basic knowledge on the structural, functional and dynamic properties of the fundamental unit of living organisms both of prokaryotic and of eukaryotes cells, in its various expressions, of the main constituents of this and of the extracellular milieu, with particular reference to the chemical composition and to the metabolic transformations to which the constitutive biomolecules undergo under physiological conditions, to the life cycle and to the principles that manage the transmission of the hereditary traits of living organisms. Within the overall training, the course aims to provide the learner with the knowledge necessary to address the study of other disciplines, including physiology, general pathology and pharmacology, as well as being preliminary to more clinical courses. The student will be able to integrate the theoretical and practical nursing knowledge with the basic biological sciences useful for understanding the complexity of individuals of all ages, groups and communities.
The course proposes an integration of the most current notions of cellular biology, biochemistry, genetics, molecular biology, microbiology and clinical biochemistry, that will provide the student with the necessary tools to get to know and describe in an organic way the structure of eukaryotic cells and their functions.

Contents

The world of the living things. Procaryotic and eukaryotic cells
Biological membrans and cell trafficking
DNA structures and functions
DNA replication genes and genomes
Different types of RNA
RNA synthesis and processing
From genes to protein: Protein synthesis
Cell cycle, mitosis and meiosis
Stem cells and regenerative medicine
The water
electrolytes,
Buffers, buffer systems of the blood
water homeostasis
The amino acids and the peptide bond
The proteins and their various functions
Hemoglobin and oxygen transport
the enzymes
Bioenergetics and oxidative phosphorylation
Structure and metabolism of carbohydrates
Structure and lipid metabolism
Communication between cells and signal transduction
Metabolic effects of insulin and glucagon
Origin and evolution of microorganisms
General aspects of the bacterial cell
Bacterial constituents: nucleoids, membranes, cell wall, capsules, flagellas, fimbrias
Spores
Growth and cultivation of bacteria
Elements of bacterial genetics (Transformation, transduction, conjugation, plasmids, mutations)
Descriptions of Disinfection and Sterilization
General antibiotic mechanisms and principles of antibiotic resistance
The pathogenicity mechanisms of microorganisms
Viruses: generality on structure, replication mechanism, nucleic acids, mechanisms of pathogenicity action
General on parasites: malaria and echinococcus
General information on staphylococci, streptococci, neisserie, enterobacteria (Salmonella, E. coli), Helicobacter, vibrions, anaerobic infections, mycobacteria, chlamydia, mycoplasma, treponema, brucellosis, bacillus
General on HIV, Hepatitis, Retrovirus, Herpes
Principles of Clinical Microbiology: The Microbiological Standard: Methods of Collection and Treatment
Respiratory infections
Urogenital infections
Gastrointestinal infections
Genes in families and populations
Structure and function of the human genome
Model organisms, comparative genomics and evolution
Gene expression
Human genetic variability and its consequences
Strategies for the identification of disease genes in monogenic and complex diseases
Genetic approaches for disease therapy
Cancer genetics
Gene / environment interactions in human diseases and traits
Farmacogenomics
Bioinformatics tecniques
I

Recommended Bibliography

Methods of Provision

Conventional

Teaching Methods

Lectures with computer media. Ongoing questions about various topics will be administered. These shall represent self-evaluation by the student, talking points and request of tutoring.
The professor is available to clarify doubts raised by the students and to carry out tutoring support for exam preparation

Contacts/More Information

Availability of the lectures slides

BIOLOGY, BIOCHEMISTRY AND MICROBIOLOGY

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Course year: 2

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BIOLOGY, BIOCHEMISTRY AND MICROBIOLOGY