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The course aims at giving the student basic information on the main features of living organisms. In particular, the student will have to acquire knowledges about the structure, function and turnover of biomolecules and the flow of information, from genome to proteoma. In addition, the student will learn about cell structure (procariotic and eukaryotic), cellular compartmentalization and cell division and communication processes. The aim of this module is to convey the knowledge of biology from the molecular to the complexity of the more complex biological systems. The course is aimed at the knowledge of the biological bases needed to understand the structure and function of the human body under normal conditions for the maintenance of health and the correct application of translational scientific research.; In particular, the course will be based on an experimental approach to develop in the learners the scientific rigor and the formulation of hypotheses, skills that will make the student open in later clinical trials to solve problems and acquire good clinical abilities.
Introduction Biological macromolecules: proteins, lipids, carbohydrates and nucleic acids Prokaryotic and Eukaryotic organization Cell function and organization: Cell membranes, cells and organelles Cytoskeleton and cell motility Chromatin and chromosomes DNA replication Transcription and the Genetic Code RNA Processing Translation and Protein Sorting Regulation of Gene Expression Cell cycle, Mitosis and Meiosis Stem cells and regenerative medicine
Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P. Molecular Biology of The Cell, Karp G: Cell and Molecular Biology: Concepts and Experiments
