During the course, the general bases of the organization of the hive "superorganism" and the systems adopted by honeybees to combat diseases will initially be described. The basics on the pathologies and symptoms detectable in the apiary, good breeding practices, the health management of the apiary and the differential diagnosis between the main circulating diseases and the permitted therapy will be provided. The specific etiological, epidemiological, pathogenetic, diagnostic and control strategies will be described for each single disease.