At the end of the course the student has knowledge of the pathogenesis of diseases of cartilage, bone and and tendons, including interactions with the clinical symptoms and the medical and surgical therapies. The student is able to navigate the stategica therapeutic and knows the classic novel therapies based on the system of biomaterials, scaffolds, stem cells, platelet concentrate, principals that are applied on the locomotor apparatus to reduce the impact of the traumatic diseases of origin also sports as well as degenerative diseases.