Basics of chemistry and biology.
The course provides an introduction to essential concepts of genetics. The coures objectives are: - to learn the language and basic concepts of genetics - to understand how traits are inherited - to learn probability concepts and use these concepts to solve problems - to understand how genetic problems may lead to disease - to understand the molecular basis of genetics (including such topics as replication, transcription, translation and mutation) - to learn the basic concepts of population genetics
Contents : 1)Mendelian Genetics a) Gregor Mendel b) Mendel’s Laws c) Monohybrid Cross d) Dihybrid Cross e) Trihybrid Cross f ) Pedigree Analysis 2)Exensions/Exceptions to Mendelian Ratios a) Multiple Alleles b) Incomplete Dominance c) Codominance d) Lethal Alleles e) Epistasis f) Penetrance g) Pleiotropy h) Phenocopy i) Mitochondrial Genes 3)Nucleotide mutations: Point Mutations, base-pair insertions or deletions 4)Sex chromosomes a) Differences of X and Y chromosomes b) X inactivation c) Genomic Imprinting 5)Cytogenetics a) Karyotypes b) Polyploidy c) Aneuploidy d) Duplications, Deletions 6) Population genetics a) genotype and allele frequencies using the Hardy-Weinberg equation.
GENETICS: A MOLECULAR APPROACH
