BIOLOGICAL CHEMISTRY
Three multiple choice tests and a final oral exam.
Basic principles of Biochemistry and Molecular Biology are necessary to study biological subjects like Physiology as well as all other subjects (Pharmacology, Medicinal Chemistry, etc.) dealing with interactions of biological systems with exogenous compounds, like drugs. The course of Biochemistry is aimed to give basic concepts necessary to understand biological processes al molecular level, turning attention particularly to structure and functions of biological macromolecules, as well as to the mechanisms by which living organisms utilize energy containing compounds.
Biomolecules. Protein structure. Structure and function of Mioglobin and Hemoglobin. General properties of enzymes and funtamentals of enzyme kinetics. Biomembrane structure and mechanisms of solute transport. Overview of metabolism and high-energy compounds. Main degradative and biosynthetic pathways of sugars, fatty acids, aminoacids and nucleotides. The Citric acid cycle and oxidative phosphorylation. DNA structure and replication. RNA transcription and processing. Regulation of gene expression. The genetic code and protein synthesis.
Recommended readings:
T.M. Devlin "Textbook of Biochemistry with Clinical Correlations", John Wiley & Sons, 2012.
D.L. Nelson, M.M. Cox "Lehninger Principles of Biochemistry", Freeman and Co., 2008.
J.M. Berg, J.L. Tymoczko, L. Stryer "Biochemistry", Freeman and Co., 2012.
D. Voet, J. G. Voet, C.W. Pratt "Principles of Biochemistry", Wiley 2008.
Course materials: lecture slides in PDF format
Face to face lectures supported by projection of educational material. Interactive discussion of the lecture subjects.
1) Readiness to offer individual assistance also in English language to incoming students
2) Availability of supporting material and bibliographic references also in english and french language.
List:Lecture slides in PDF format
3) Readiness to accept examination of incoming students also in a foreign language (English and French)