Preformulation: concepts of physics of compression, crystalline state, thermal analysis(DSC, TG), solubility and dissolution rate of drugs.
Controlled release: pharmaceutical polymers, biodegradable polymers, controlled release systems (reservoirs, matrices, osmotic pumps, chemical systems), pharmaceutical delivery systems for peptide and proteins, liposomes, nanoparticles, drug targeting.
Concepts of chronobiology and chronotherapy for the development of chronotherapeutic formulations.
Biopharmaceutics: basic concepts of pharmacokinetics; mechanisms of drug absorption; bioavailability and bioequivalence; Biopharmaceutical Classification System (BCS).
