At the end of this course, the student will know the role of biochemical parameters in biological samples as well as in vivo at different levels of structural organization, from single molecules to cells, and in the whole organism both in the humans and in animals. The student will be able to know and manage: the role of the biochemical parameters that are the basis of inherited and acquired genetic diseases; the quality control system, the clinical molecular biology methodologies for the assessment of disease susceptibility; the automation technologies for the quantitative and qualitative analysis of the biochemical parameters useful for clinical diagnostics.