The course is aimed at drawing the attention on the unequal distribution of wealth and economic development al global level. Deterritorialization and globalization highlight new geopolitical scenarios that find evidence in new and consolidated theories. The geographical analysis of economics, politics and space will represent useful tools for understanding the world-system. Useful instruments will be provided to understand and read critically to-date organization and possible future evolution of international trade relations, related to the influence of the geographical data and spatial conditions typical of regional economical situations.