METHODOLOGIES IN INORGANIC CHEMISTRY

Single discipline educational activity

Course Sheet

Academic Year of enrolment:

2015/2016

Type of Course:

Related/Supplementary

Optional/Mandatory:

Optional

Degree:

Master's Degree Programme in CHEMICAL SCIENCES

Disciplinary Sector:

General and Inorganic Chemistry

Credits:

Programme Year:

Professor and Collaborators:

ZUCCA Antonio

Hours of classroom activity:

Prerequisites:

SYNTHESIS AND CHARACTERISATION OF COORDINATION COMPOUNDS
The unit requests knowledge of the topics treated in the courses of Inorganic Chemistry.

ADVANCED ORGANIC SYNTHESIS
Good knowledge of basic organic chemistry

MASS SPECTROMETRY HYPHENATED TECHNIQUES
The unit can be fruitfully attended only by students bearing at least a basic knowledge of analytical chemistry, instrumental analysis and statistics applied to analytical measures

AF code:

40001137

Assessment Methods

Verification of learning:

SYNTHESIS AND CHARACTERISATION OF COORDINATION COMPOUNDS
Final oral exam

ADVANCED ORGANIC SYNTHESIS
Final oral examination, evaluation of laboratory activities, writing of a report.

MASS SPECTROMETRY HYPHENATED TECHNIQUES
As a general rule, the exam is oral. It can be completely (or partially) vicarage by the results of the written tests which will permitted only to students that regularly have attended lessons.

Teaching period

Second semester

Objectives

SYNTHESIS AND CHARACTERISATION OF COORDINATION COMPOUNDS
Objective of the course is to teach some basic aspects of the synthesis and characterization of coordination compounds.
At the end of the course the student will have gained knowledge related to the principal syhnthetic methods and characterization of coordination compounds of transition metals. In particular, the student will have knowledge of the basic principles and applications of NMR spectroscopy to the study of metal complexes in solution. The student will be able to analyse an NMR spectrum and correlate it to the molecular structure of the corresponding coordination compound.

ADVANCED ORGANIC SYNTHESIS
Objective of the course is to teach both basic aspects and recent results of research activity in the field of polar organometallic chemistry with application to organic synthesis. The laboratory experiences will introduce students to the handling and manipulation of substances sensitive to air and moisture.

MASS SPECTROMETRY HYPHENATED TECHNIQUES
At the end of the course students will have gained skills related to general and applicative aspects of the principal mass spectrometry hyphenated techniques like GC-MS, HPLC-MS and ICP-MS.

Contents

SYNTHESIS AND CHARACTERISATION OF COORDINATION COMPOUNDS
Synthetic methods of coordination compounds. Addition, substitution and redox reactions. Oxidative addition and reductive elimination. Reaction of coordinated ligands.
Spectroscopic methods of analysis of coordination compounds. NMR spectroscopy in Inorganic Chemistry: chemical shift, spin-spin coupling, signal multiplicity. NMR active nuclei, isotopic abundance and satellites.
Fluxionality: time scale of instrumental methods. IR and NMR spectra of fluxional species.
Characterization of inorganic and organometallic compounds

ADVANCED ORGANIC SYNTHESIS
Using organometallic reagents to make carbon-carbon bonds. Carbon-metal bonds in polar organometallic compounds. Preparation and employment of Grignard reagents. Preparation and employment of organo-lithium, -sodium and –potassium reagents. Generation of polar organometallic reagents under Birh reduction conditions.

MASS SPECTROMETRY HYPHENATED TECHNIQUES
As far as the teaching unit of Mass Spectrometry Hyphenated Techniques is concerned, the contents of the course are: coupling of chromatographic techniques with MS. Overview on the instruments. GC-MS coupling, HPLC-MS coupling, SFC-MS coupling (hints), ICP-OES (hints), ICP-MS coupling

Recommended Bibliography

SYNTHESIS AND CHARACTERISATION OF COORDINATION COMPOUNDS
Power point slides.
J.E. Huheey, E.A.Keiter, R.L.Keiter, Inorganic Chemistry, 4th ed.; HarperCollins 1993.
R.H.Crabtree, The Organometallic Chemistry of the Transition Metals, J.Wiley
P.S. Pregosin, NMR in Organometallic Chemistry, Wiley-VCH 2012.

ADVANCED ORGANIC SYNTHESIS
M. Schlosser, Organometallics in Synthesis, 2012, Wiley
Power Point presentations, selection of scientific papers

MASS SPECTROMETRY HYPHENATED TECHNIQUES
Suggested texts:
1. R. Kellner, J.-M. Mermet, M. Otto, H.M. Widmar, Chimica Analitica, EdiSES, 2003
2. Power point presentations used in the face-to-face lessons, selected papers and reviews

Teaching Methods

SYNTHESIS AND CHARACTERISATION OF COORDINATION COMPOUNDS
Face to face lessons. Interpretation of NMR spectra of coordination compounds.

ADVANCED ORGANIC SYNTHESIS
Academical lessons, exercises, laboratory practice.

MASS SPECTROMETRY HYPHENATED TECHNIQUES
All topics will be treated on face to face lessons.

Contacts/More Information

1) Readiness to offer individual assistance also in English language to incoming students

2) Availability of supporting material and bibliographic references also in english language

3) Readiness to accept examination of incoming students also in a foreign language (English)

METHODOLOGIES IN INORGANIC CHEMISTRY

Course year: 1

Course year: 2

Search form

METHODOLOGIES IN INORGANIC CHEMISTRY