General etiology. Molecular pathology of proteins, carbohydrates, lipids and nucleic acids. Reversible and irreversible damage. Cell injury and adaptation to injury.Cellular stress: mechanisms of induction and protective. Degenerative processes. Cell death: necrosis and apoptosis. Acute inflammation. Chemicals mediators of inflammatory process. Cronic inflammation and associated deseases. Genetic pathology: transmission mechanisms and molecular diagnosis of hereditary diseases. Oncology: morphology and properties of neoplastic cells. Chemical , physical and viral carcinogenesis. Molecular mechanisms of carcinogenesis. Oncogenes and tumor suppressor genes. Metastasis and angiogenesis. Cancer stem cells. Biological besis of cancer therapies. Genomics in oncology.