At the end of the course, the student will be able to: describe the diagnostic laboratory, according to the main moments: pre-analytical, analytical and post-analytical; to describe the diagnostic significance of the main laboratory investigations; to know the problems related to the preparation of the patient, the collection and storage of the samples; to describe the principles of analytical measurement in Clinical Biochemistry; to find the meaning and use of laboratory investigations in connection with diseases of the major organs and systems.